Chronic wounds are on the rise and represent an enormous financial burden to the patient and to the healthcare system. Wound related infection is a serious complication, which increases the risk of hospitalization and often leads to amputation. Placental membranes have a long history of use for management of wounds. One of the properties of placental membranes in utero is to protect the fetus from infections. However, limited availability and short shelf-life precluded the widespread use of fresh placental tissues. Progress in tissue preservation resulted in fast commercialization of placental membranes. However, preservation techniques can lead to varying degrees of damage to the tissue components, and therefore affect the functional properties of placental membranes.
In the published study, antimicrobial properties of human cryopreserved viable amniotic membrane
(hCVAM) were investigated. This study was conducted in the laboratory of
"Deficiencies in chronic wound environment preclude wound closure leading to high risk for wound infection. Therefore, wound care modalities should not only support natural wound repair process, but also possess antimicrobial properties. Results of the study indicate that the cryopreserved viable placental amnion retains both properties of the native tissue," says Professor
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